Pressor effects of epinephrine, norepinephrine and desoxycorticosterone acetate weakened by sodium withdrawal.
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چکیده
منابع مشابه
Effects of adrenal steroid withdrawal on chronic renovascular hypertension in adrenalectomized sheep.
Adrenalectomized sheep with a single kidney were maintained chronically hypertensive after renal arterial constriction on a maintenance dosage of desoxycorticosterone acetate and cortisone acetate. This level of steroid support is totally without pressor effects in adrenalectomized animals with normal kidneys. Blood pressure was monitored after steroid withdrawal with (1) no replacement of Na l...
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To evaluate the effect of chronic hyperinsulinemia on blood pressure in salt-dependent hypertension, we infused insulin (1.0 IU/d, n = 15) or saline (n = 13) for 4 weeks into deoxycorticosterone acetate-salt hypertensive rats. The insulin infusion increased plasma insulin levels to 24 +/- 2 microU/mL, which was higher than in the saline-infused rats (9 +/- 1 microU/mL) but was still within the ...
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We assessed the release of neuronal and adrenomedullary catecholamines in response to various stimuli of the sympathetic nervous system in normal subjects. Plasma catecholamines and their urinary metabolites, normetanephrine and metanephrine, were measured. Sodium restriction increased supine plasma norepinephrine by 37% and ambulatory plasma norepinephrine by 22%, with urinary normetanephrine ...
متن کاملA specific increase in cardiovascular reactivity related to sodium retention in DOCA-salt-treated rats.
1. Exchangeable body sodium was measured in deoxycorticosterone acetate (DOCA) -salt-treated rats by whole body y-counting after equilibration with a "Na isotope. 2. The blood pressure of DOCA-salt-treated rats is positively correlated with their exchangeable body sodium. 3. After pithing, the heart rate is significantly lower in DOCA-salt-treated than in control rats: in conscious DOCA-salt-tr...
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ورودعنوان ژورنال:
- Circulation
دوره 6 3 شماره
صفحات -
تاریخ انتشار 1952